A healthy future is possible.

Take action now, and you may help prevent asthma from occurring in children.

6.3 million children

Childhood asthma affects over 6 million children nationwide, and nearly 1 million of those children are under 4 years of age. But, asthma doesn’t just spring up overnight. It starts out as wheezing illnesses and as a child grows, so does the disease that may follow him or her around for a lifetime. Asthma is the most common chronic disease in childhood, and causes nearly 14 million missed school days and most unexpected hospital visits each year nationwide.

What if there was a chance to reduce early wheezing and in doing so, reduce asthma later in life?

That’s what the ORBEX Clinical Study aims to do. The purpose of the ORBEX Clinical Study is to test to see if a medication can help prevent the development of wheezing in young children.


Asthma and Wheezing in Children

According to the National Heart, Lung and Blood Institute, an institute in the National Institutes of Health, asthma is a chronic lung disease that inflames and narrows a person’s airways. There is currently no cure for asthma, and while it affects people of all ages, it most often starts during childhood. Symptoms include chest tightness, shortness of breath and coughing.

In 2014, there were 24 million people living with asthma in the United States - 17.7 million adults and 6.3 million children (under 18 years of age). Asthma affects children between the ages of 5 and 14 at a higher rate. Asthma can also appear in young children before the age of 5, but is often harder to diagnose. This is because asthma symptoms may occur with other conditions such as a cold or respiratory infections. However, an early indicator of asthma in young children is wheezing.


According to the National Institutes of Health a young child who has frequent wheezing with colds or respiratory infections is more likely to have asthma if:

  • One or both parents have asthma;
  • Child has signs of allergies;
  • Child has eczema (children with eczema are 46% more likely to develop asthma1);
  • Child has allergic reactions to pollens or other airborne allergens; and
  • Child wheezes even when he/she does not have a cold or other infection.

1 Carlsen, B. C., Menne, T., and Johansen, J. D. 20 Years of standard patch testing in an eczema population with focus on patients with multiple contact allergies. Contact Dermatitis, 2007, 57: 76-83.